Reactome | D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm]

Schema > Complex > Entries

D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-MMU-5685826] D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] - Mus musculus
consumedByEvent	[Reaction:R-MMU-5685838] CX3 complex binds D-loop structures - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10061065
displayName	D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm]
hasComponent	[Complex:R-MMU-5685316] BCDX2 complex [nucleoplasm] [Complex:R-MMU-5685655] BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] [DefinedSet:R-MMU-5685980] EXO1,DNA2:BLM,WRN [nucleoplasm] [OtherEntity:R-ALL-83893] Heteroduplex DNA with D-loop structure with extended pairing between invading strand and complementary heteroduplex strand [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-9735494] Kat5 [nucleoplasm] [Complex:R-MMU-5682166] p-MRN [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-5693527] phospho-Atm [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-5687710] phospho-p-S990,Ac-K1249-BRIP1 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-5685658] D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] - Homo sapiens
maxDepth	6
name	D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1
producedByEvent	[Reaction:R-MMU-5693620] D-loop formation mediated by PALB2, BRCA2 and RAD51 - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-5685658
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(output)	[Reaction:R-MMU-5693620] D-loop formation mediated by PALB2, BRCA2 and RAD51
(input)	[Reaction:R-MMU-5685838] CX3 complex binds D-loop structures
(hasComponent)	[Complex:R-MMU-5685826] D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm]
(inferredTo)	[Complex:R-HSA-5685658] D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm]

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