Reactome | Hoxa1 gene is transcribed

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Hoxa1 gene is transcribed Show undefined attributes

authored	[InstanceEdit:5621561] May, Bruce, 2014-08-31 [InstanceEdit:6810137] Rezsohazy, Ren�, 2015-11-15
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:5617923] May, Bruce, 2014-08-16
dbId	5617999
displayName	Hoxa1 gene is transcribed
edited	[InstanceEdit:5621561] May, Bruce, 2014-08-31
followingEvent	[BlackBoxEvent:R-MMU-5617955] Hoxa1 mRNA is translated - Mus musculus
input	[EntityWithAccessionedSequence:R-MMU-5617428] Hoxa1 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5617912] Epigenetic regulatory mechanisms distinguish retinoic acid-mediated transcriptional responses in stem cells and fibroblasts [LiteratureReference:5617921] The retinol signaling pathway in mouse pluripotent P19 cells [LiteratureReference:5617996] Retinoids regulate stem cell differentiation [LiteratureReference:5617936] Retinoic acid-responsive enhancers located 3' of the Hox A and Hox B homeobox gene clusters. Functional analysis [LiteratureReference:5617961] High histone acetylation and decreased polycomb repressive complex 2 member levels regulate gene specific transcriptional changes during early embryonic stem cell differentiation induced by retinoic acid [LiteratureReference:5619332] Evolutionary-conserved enhancers direct region-specific expression of the murine Hoxa-1 and Hoxa-2 loci in both mice and Drosophila [LiteratureReference:5619244] In vivo functional analysis of the Hoxa-1 3' retinoic acid response element (3'RARE) [LiteratureReference:5675600] Detection of targeted GFP-Hox gene fusions during mouse embryogenesis [LiteratureReference:5675603] Hox-1.6: a mouse homeo-box-containing gene member of the Hox-1 complex [LiteratureReference:5675596] Expression of the mouse labial-like homeobox-containing genes, Hox 2.9 and Hox 1.6, during segmentation of the hindbrain [LiteratureReference:5675625] Region-specific expression in early chick and mouse embryos of Ghox-lab and Hox 1.6, vertebrate homeobox-containing genes related to Drosophila labial [LiteratureReference:5687966] Identification of a retinoic acid responsive enhancer 3' of the murine homeobox gene Hox-1.6 [LiteratureReference:5687920] linc-HOXA1 is a noncoding RNA that represses Hoxa1 transcription in cis [LiteratureReference:5688604] Hoxa1 lineage tracing indicates a direct role for Hoxa1 in the development of the inner ear, the heart, and the third rhombomere
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Hoxa1 gene is transcribed
orthologousEvent	[BlackBoxEvent:R-HSA-5617471] HOXA1 gene is transcribed - Homo sapiens
output	[EntityWithAccessionedSequence:R-MMU-5617929] Hoxa1 mRNA [cytosol]
precedingEvent	[BlackBoxEvent:R-MMU-5617990] Retinoic acid activates Hoxa1 chromatin - Mus musculus
regulatedBy	[PositiveRegulation:R-MMU-5634077] Positive regulation by 'atRA:Rara,g:Rxra at active Hoxa1 chromatin [nucleoplasm]'
regulationReference	[RegulationReference:9642721] Positive regulation by 'atRA:Rara,g:Rxra at active Hoxa1 chromatin [nucleoplasm]' Evolutionary-conserved enhancers direct region-specific expression of the murine Hoxa-1 and Hoxa-2 loci in both mice and Drosophila
releaseDate	2015-12-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5693642] Blasi, F, 2015-05-13
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-5617999
summation	[Summation:5621677] The Hoxa1 gene is transcribed to yield mRNA in response to r...

Referrals

(precedingEvent)

[BlackBoxEvent:R-MMU-5617955] Hoxa1 mRNA is translated

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