Reactome | DAG and Ca+2 bind to PKC and tether it to membrane

Schema > Reaction > Entries

DAG and Ca+2 bind to PKC and tether it to membrane Show undefined attributes

category	binding
compartment	[Compartment:13231] nuclear envelope [Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10053066
displayName	DAG and Ca+2 bind to PKC and tether it to membrane
eventOf	[Pathway:R-MMU-4419969] Depolymerization of the Nuclear Lamina - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Depolymerisation:R-MMU-5229194] Depolymerization of lamin filaments after PKC-mediated phosphorylation - Mus musculus
inferredFrom	[Reaction:R-HSA-5223304] DAG and Ca+2 bind to PKC and tether it to membrane - Homo sapiens
input	[SimpleEntity:R-ALL-29496] Ca2+ [nucleoplasm] [SimpleEntity:R-ALL-5221124] DAG [nuclear envelope] [DefinedSet:R-MMU-5223295] p-PKCA, p-PKCB [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	DAG and Ca+2 bind to PKC and tether it to membrane
output	[Complex:R-MMU-5223297] DAG:active PKC:Ca+2 [nuclear envelope]
precedingEvent	[Reaction:R-MMU-5218805] PKC autophosphorylates - Mus musculus [Reaction:R-MMU-5221130] LPIN catalyzes conversion of phosphatidic acid to diacylglycerol - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-5223304
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-4419969] Depolymerization of the Nuclear Lamina
(precedingEvent)	[Depolymerisation:R-MMU-5229194] Depolymerization of lamin filaments after PKC-mediated phosphorylation
(inferredTo)	[Reaction:R-HSA-5223304] DAG and Ca+2 bind to PKC and tether it to membrane

Cite Us!