Reactome | Vangl2 is phosphorylated in response to Wnt5a

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Vangl2 is phosphorylated in response to Wnt5a Show undefined attributes

authored	[InstanceEdit:4549500] Rothfels, K, 2013-09-12
catalystActivity	[CatalystActivity:5250910] protein serine/threonine kinase activity of unknown kinase [cytosol]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:4551569] Rothfels, K, 2013-09-13
dbId	4551572
displayName	Vangl2 is phosphorylated in response to Wnt5a
edited	[InstanceEdit:4663813] Matthews, L, 2013-10-07
input	3 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-MMU-4551499] N4GlycoAsn-PalmS-Wnt5a:Ror2:Vangl2 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:4551418] Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Vangl2 is phosphorylated in response to Wnt5a
orthologousEvent	[Reaction:R-HSA-4551570] VANGL2 is phosphorylated in response to WNT5A - Homo sapiens
output	3 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-MMU-4551500] N4GlycoAsn-PalmS-Wnt5a:Ror2:p-Vangl2 [plasma membrane]
precedingEvent	[Reaction:R-MMU-4551566] Wnt5a binds Ror2 and Vangl2 - Mus musculus
releaseDate	2013-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5099870] Kikuchi, Akira, 2013-11-12
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-4551572
summation	[Summation:4551568] Vangl2 is multiply phosphorylated on two clusters of serine ...
updateTrackers	[UpdateTracker:9786711] Update Tracker - [Reaction:4551572] Vangl2 is phosphorylated in response to Wnt5a - v48:[add_removeCatalystActivity]

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(updatedInstance)

[UpdateTracker:9786711] Update Tracker - [Reaction:4551572] Vangl2 is phosphorylated in response to Wnt5a - v48:[add_removeCatalystActivity]

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