Reactome | PIP3 stimulates Vav1

Schema > Reaction > Entries

authored	[InstanceEdit:435013] Akkerman, JW, 2009-09-04
category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:434636] Jupe, S, 2009-09-02
dbId	434629
displayName	PIP3 stimulates Vav1
edited	[InstanceEdit:870420] Jupe, S, 2010-06-08
input	[SimpleEntity:R-ALL-179838] PI(3,4,5)P3 [plasma membrane] [EntityWithAccessionedSequence:R-MMU-434625] Vav1 [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:389304] Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PIP3 stimulates Vav1
orthologousEvent	[Reaction:R-HSA-434637] PI(3,4,5)P3 binds VAV1,2,3 - Homo sapiens
output	[Complex:R-MMU-434628] PIP3:Vav1 [cytosol]
releaseDate	2010-09-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:445668] Poole, AW, 2009-11-02 [InstanceEdit:445653] Jones, ML, 2009-11-02 [InstanceEdit:445649] Harper, MT, 2009-11-02
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-434629
summation	[Summation:434631] Vav interacts directly with PIP2 and PIP3, with a fivefold s...

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