Reactome | Shp2 binds pUnc5C

Schema > Reaction > Entries

authored	[InstanceEdit:374705] Garapati, P V, 2008-07-30 10:24:23
category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:418861] Garapati, P V, 2009-04-27 09:27:02
dbId	418862
displayName	Shp2 binds pUnc5C
edited	[InstanceEdit:374705] Garapati, P V, 2008-07-30 10:24:23
input	[Complex:R-MMU-418819] Netrin-1:pUnc5:DCC [plasma membrane] [EntityWithAccessionedSequence:R-MMU-210002] Ptpn11 [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:418682] Netrin signaling leading to directed growth cone steering [LiteratureReference:418743] Netrin stimulates tyrosine phosphorylation of the UNC-5 family of netrin receptors and induces Shp2 binding to the RCM cytodomain
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Shp2 binds pUnc5C
orthologousEvent	[Reaction:R-HSA-418863] Shp2 binds pUnc5C - Homo sapiens
output	[Complex:R-MMU-418824] Netrin-1:pUnc5C:DCC:Shp2 [plasma membrane]
releaseDate	2010-06-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:513006] Cooper, HM, 2010-02-16
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-418862
summation	[Summation:418759] PTPN11 (SHP2) is recruited to the phosphorylated UNC5C recep...
updateTrackers	[UpdateTracker:9779673] Update Tracker - [Reaction:418862] Shp2 binds pUnc5C - v65:[modifyText]

(updatedInstance)

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