Reactome | Rnd1 interacts with Plexin-B1:Sema4D

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Rnd1 interacts with Plexin-B1:Sema4D Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10014017
displayName	Rnd1 interacts with Plexin-B1:Sema4D
eventOf	[Pathway:R-MMU-416550] Sema4D mediated inhibition of cell attachment and migration - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-416562] p190RhoGAP binds Plexin-B1 - Mus musculus [Reaction:R-MMU-416546] Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity - Mus musculus
inferredFrom	[Reaction:R-HSA-400677] Rnd1 interacts with Plexin-B1:Sema4D - Homo sapiens
input	[Complex:R-MMU-421104] RND1:GTP [plasma membrane] [Complex:R-MMU-419621] SEMA4D:MET:p-Y-PLXNB1 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Rnd1 interacts with Plexin-B1:Sema4D
output	[Complex:R-MMU-416587] SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane]
precedingEvent	[Reaction:R-MMU-400682] Active Rac1 interacts with Plexin-B1:Sema4D - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-400677
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-416550] Sema4D mediated inhibition of cell attachment and migration
(precedingEvent)	[Reaction:R-MMU-416562] p190RhoGAP binds Plexin-B1 [Reaction:R-MMU-416546] Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity
(inferredTo)	[Reaction:R-HSA-400677] Rnd1 interacts with Plexin-B1:Sema4D