Reactome | Semaphorin interactions

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Semaphorin interactions Show undefined attributes

created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10100005
displayName	Semaphorin interactions
eventOf	[Pathway:R-MMU-422475] Axon guidance - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-MMU-400685] Sema4D in semaphorin signaling - Mus musculus [Pathway:R-MMU-399955] SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion - Mus musculus [Pathway:R-MMU-399954] Sema3A PAK dependent Axon repulsion - Mus musculus [Pathway:R-MMU-399956] CRMPs in Sema3A signaling - Mus musculus [Pathway:R-MMU-416700] Other semaphorin interactions - Mus musculus
inferredFrom	[Pathway:R-HSA-373755] Semaphorin interactions - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	Semaphorin interactions
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-373755
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-422475] Axon guidance
(hasEncapsulatedEvent)	[Pathway:R-MMU-8848021] Signaling by PTK6 [Pathway:R-MMU-5627117] RHO GTPases Activate ROCKs
(inferredTo)	[Pathway:R-HSA-373755] Semaphorin interactions

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