Reactome | Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)

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Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) Show undefined attributes

authored	[InstanceEdit:2142839] Williams, MG, 2012-02-24
created	[InstanceEdit:2142724] Williams, MG, 2012-02-24
dbId	2142816
displayName	Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
edited	[InstanceEdit:2142839] Williams, MG, 2012-02-24
eventOf	[Pathway:R-HSA-2142753] Arachidonate metabolism - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:2162255] omega-hydroxylase P450 pathway
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-2161795] Arachidonate is hydroxylated to 16-HETE by CYP(1) - Homo sapiens [Reaction:R-HSA-9915992] Arachidonate is hydroxylated to 17-HETE by CYP(1) - Homo sapiens [Reaction:R-HSA-9915993] Arachidonate is hydroxylated to 18-HETE by CYP(1) - Homo sapiens [Reaction:R-HSA-2161814] Arachidonate is hydroxylated to 19-HETE by CYP(2) - Homo sapiens [Reaction:R-HSA-2161940] Arachidonate is hydroxylated to 20-HETE by CYP(3) - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2162141] Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase [LiteratureReference:2162148] Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology [Book:2142759] Vance, Dennis E 978-0-444-53219-0 Biochemistry of Lipids, Lipoproteins and Membranes, 5th Edition The eicosanoids: cyclooxygenase, lipoxygenase, and epoxygenase pathways
maxDepth	2
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
orthologousEvent	[Pathway:R-DDI-2142816] Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) - Dictyostelium discoideum [Pathway:R-CEL-2142816] Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) - Caenorhabditis elegans [Pathway:R-DME-2142816] Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) - Drosophila melanogaster [Pathway:R-GGA-2142816] Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) - Gallus gallus [Pathway:R-XTR-2142816] Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) - Xenopus tropicalis [Pathway:R-DRE-2142816] Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) - Danio rerio [Pathway:R-SSC-2142816] Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) - Sus scrofa [Pathway:R-BTA-2142816] Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) - Bos taurus [Pathway:R-CFA-2142816] Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) - Canis familiaris [Pathway:R-RNO-2142816] Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) - Rattus norvegicus [Pathway:R-MMU-2142816] Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) - Mus musculus
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2012-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2569042] Rush, MG, 2012-11-10 [InstanceEdit:9917333] Hill, David P, 2024-08-02
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-2142816
summation	[Summation:2162145] Similar to the lipoxygenases, cytochrome P450 (CYP) enzymes ...
updateTrackers	[UpdateTracker:9919452] Update Tracker - [Pathway:2142816] Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) - v90:[modifyText, removeHasEvent]

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(updatedInstance)	[UpdateTracker:9919452] Update Tracker - [Pathway:2142816] Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) - v90:[modifyText, removeHasEvent]
(hasEvent)	[Pathway:R-HSA-2142753] Arachidonate metabolism

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