Reactome | Activation of alpha-linolenic acid to alpha-linolenoyl-CoA

Schema > Reaction > Entries

Activation of alpha-linolenic acid to alpha-linolenoyl-CoA Show undefined attributes

catalystActivity	[CatalystActivity:10041085] long-chain fatty acid-CoA ligase activity of ACSL1 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10041087
displayName	Activation of alpha-linolenic acid to alpha-linolenoyl-CoA
eventOf	[Pathway:R-MMU-2046106] alpha-linolenic acid (ALA) metabolism - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-2046084] Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA - Mus musculus
inferredFrom	[Reaction:R-HSA-2046085] Activation of alpha-linolenic acid to alpha-linolenoyl-CoA - Homo sapiens
input	[SimpleEntity:R-ALL-2046056] ALA [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-211579] ATP [endoplasmic reticulum membrane] [SimpleEntity:R-ALL-162743] CoA-SH [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	Activation of alpha-linolenic acid to alpha-linolenoyl-CoA
output	[SimpleEntity:R-ALL-2046064] adenosine 5'-monophosphate [endoplasmic reticulum membrane] [SimpleEntity:R-ALL-2046062] ALA-CoA [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-2046049] PPi [endoplasmic reticulum membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-2046085
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-2046106] alpha-linolenic acid (ALA) metabolism
(precedingEvent)	[Reaction:R-MMU-2046084] Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA
(inferredTo)	[Reaction:R-HSA-2046085] Activation of alpha-linolenic acid to alpha-linolenoyl-CoA

Cite Us!