Reactome | Acyl chain remodeling of DAG and TAG

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Acyl chain remodeling of DAG and TAG Show undefined attributes

created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10100713
displayName	Acyl chain remodeling of DAG and TAG
eventOf	[Pathway:R-MMU-1483206] Glycerophospholipid biosynthesis - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:2162179] acylglycerol acyl-chain remodeling
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-1482777] TAG is hydrolyzed to DAG by PNPLA2/3 - Mus musculus [Reaction:R-MMU-8848580] DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG - Mus musculus [Reaction:R-MMU-1482889] DAG is acylated to TAG by DGAT1/2 - Mus musculus [Reaction:R-MMU-1482811] DAG is hydrolyzed to 2-MAG by PNPLA2/3 - Mus musculus [Reaction:R-MMU-5696448] AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG - Mus musculus [Reaction:R-MMU-1482654] 2-MAG is transacylated to DAG by PNPLA2/3 - Mus musculus [Reaction:R-MMU-1482647] 2-MAG and DAG are transacylated to TAG by PNPLA2/3 - Mus musculus [Reaction:R-MMU-1482543] 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL - Mus musculus
inferredFrom	[Pathway:R-HSA-1482883] Acyl chain remodeling of DAG and TAG - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Acyl chain remodeling of DAG and TAG
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-1482883
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-1483206] Glycerophospholipid biosynthesis
(inferredTo)	[Pathway:R-HSA-1482883] Acyl chain remodeling of DAG and TAG

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