Reactome | 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL

Schema > Reaction > Entries

2-MAG is hydrolyzed to fatty acid and glycerol by MGLL Show undefined attributes

catalystActivity	[CatalystActivity:10033201] monoacylglycerol lipase activity of MGLL dimer [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10033203
displayName	2-MAG is hydrolyzed to fatty acid and glycerol by MGLL
eventOf	[Pathway:R-MMU-1482883] Acyl chain remodeling of DAG and TAG - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1482543] 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL - Homo sapiens
input	[SimpleEntity:R-ALL-1498728] 2-MAG [endoplasmic reticulum membrane] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	2-MAG is hydrolyzed to fatty acid and glycerol by MGLL
output	[SimpleEntity:R-ALL-1500593] fatty acid [endoplasmic reticulum membrane] [SimpleEntity:R-ALL-76116] Glycerol [cytosol]
precedingEvent	[Reaction:R-MMU-1482811] DAG is hydrolyzed to 2-MAG by PNPLA2/3 - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-1482543
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-1482883] Acyl chain remodeling of DAG and TAG
(inferredTo)	[Reaction:R-HSA-1482543] 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL

Cite Us!