Reactome | Carbonic anhydrase hydrates carbon dioxide (cytosol)

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Carbonic anhydrase hydrates carbon dioxide (cytosol) Show undefined attributes

catalystActivity	[CatalystActivity:10033121] carbonate dehydratase activity of CA1,2,3,7,13:Zinc [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10033127
displayName	Carbonic anhydrase hydrates carbon dioxide (cytosol)
eventOf	[Pathway:R-MMU-1475029] Reversible hydration of carbon dioxide - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1475026] Carbonic anhydrase hydrates carbon dioxide (cytosol) - Homo sapiens
input	[SimpleEntity:R-ALL-113528] CO2 [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Carbonic anhydrase hydrates carbon dioxide (cytosol)
output	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-111627] HCO3- [cytosol]
precedingEvent	[Reaction:R-MMU-70967] IDH3 complex decarboxylates isocitrate - Mus musculus [Reaction:R-MMU-450984] IDH2 dimer decarboxylates isocitrate - Mus musculus [Reaction:R-MMU-71401] OGDH dimer decarboxylates 2-OG - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-1475026
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-1475029] Reversible hydration of carbon dioxide
(inferredTo)	[Reaction:R-HSA-1475026] Carbonic anhydrase hydrates carbon dioxide (cytosol)

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