Reactome | TDPK phosphorylates ThDP to ThTP

Schema > Reaction > Entries

authored	[InstanceEdit:997388] Jassal, B, 2010-11-09
catalystActivity	[CatalystActivity:997383] thiamine-diphosphate kinase activity of TDPK [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:997388] Jassal, B, 2010-11-09
crossReference	[DatabaseIdentifier:11880392] Rhea:11241
dbId	997381
displayName	TDPK phosphorylates ThDP to ThTP
edited	[InstanceEdit:997388] Jassal, B, 2010-11-09
eventOf	[Pathway:R-HSA-196819] Vitamin B1 (thiamin) metabolism - Homo sapiens
followingEvent	[Reaction:R-HSA-965067] THTPA:Mg2+ hydrolyzes ThTP to TDP - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-29480] ThDP [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:997386] Enzyme system involved in the synthesis of thiamin triphosphate. I. Purification and characterization of protein-bound thiamin diphosphate: ATP phosphoryltransferase
modified	[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name	TDPK phosphorylates ThDP to ThTP ThDP + ATP <-> ThTP + ADP
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-964965] ThTP [cytosol]
precedingEvent	[Reaction:R-HSA-196761] 2xTPK1:Mg2+ phosphorylates THMN - Homo sapiens
releaseDate	2010-12-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:994085] D'Eustachio, P, 2010-11-05
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-997381
summation	[Summation:997384] Thiamin triphosphate (ThTP) is believed to be synthesized fr...

(hasEvent)	[Pathway:R-HSA-196819] Vitamin B1 (thiamin) metabolism
(precedingEvent)	[Reaction:R-HSA-965067] THTPA:Mg2+ hydrolyzes ThTP to TDP

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