Reactome | Unknown NAT N-acetylates kynurenine

Schema > Reaction > Entries

authored	[InstanceEdit:9971626] Stephan, Ralf, 2025-11-09
catalystActivity	[CatalystActivity:9971630] N-acetyltransferase activity of unknown NAT [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9971628] Stephan, Ralf, 2025-11-09
dbId	9971629
displayName	Unknown NAT N-acetylates kynurenine
edited	[InstanceEdit:9984514] Stephan, Ralf, 2026-03-09
eventOf	[Pathway:R-HSA-71240] Tryptophan catabolism - Homo sapiens
input	[SimpleEntity:R-ALL-76183] Ac-CoA [cytosol] [SimpleEntity:R-ALL-29970] L-KYN [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9971569] Gut-derived uremic toxin handling in vivo requires OAT-mediated tubular secretion in chronic kidney disease
maxDepth	1
modified	[InstanceEdit:9984515] Stephan, Ralf, 2026-03-09
name	Unknown NAT N-acetylates kynurenine
output	[SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-9971631] N-acetylkynurenine [cytosol]
precedingEvent	[Reaction:R-HSA-71189] AFMID hydrolyses NFK to L-KYN - Homo sapiens
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2026-03-25
releaseStatus	NEW
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9981792] D'Eustachio, Peter, 2026-02-10
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9971629
summation	[Summation:9971632] Metabolomic studies have consistently detected the presence ...

(hasEvent)

Cite Us!