Reactome | ARID1A binds SMARCC1:SMARCC2 dimer:SMARCD1:SMARCE1:SMARCB1

Schema > Reaction > Entries

ARID1A binds SMARCC1:SMARCC2 dimer:SMARCD1:SMARCE1:SMARCB1 Show undefined attributes

authored	[InstanceEdit:9934146] Rothfels, Karen, 2025-01-06
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9934025] Rothfels, Karen, 2025-01-06
dbId	9934028
displayName	ARID1A binds SMARCC1:SMARCC2 dimer:SMARCD1:SMARCE1:SMARCB1
edited	[InstanceEdit:9934146] Rothfels, Karen, 2025-01-06
eventOf	[Pathway:R-HSA-9933946] Formation of the embryonic stem cell BAF (esBAF) complex - Homo sapiens
followingEvent	[Reaction:R-HSA-9934022] DPF2, PHF10 bind SMARCC1:SMARCC2 dimer:SMARD1:ARID1A - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-389259] ARID1A [nucleoplasm] [Complex:R-HSA-9934012] SMARCC1:SMARCC2 dimer:SMARCD1:SMARCE1:SMARCB1 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9933219] An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network [LiteratureReference:9932374] An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency [LiteratureReference:9933930] Transcriptional repression by the BRG1-SWI/SNF complex affects the pluripotency of human embryonic stem cells [LiteratureReference:9933220] Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics [LiteratureReference:9933957] GBAF, a small BAF sub-complex with big implications: a systematic review [LiteratureReference:9933218] COMPASS and SWI/SNF complexes in development and disease
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	ARID1A binds SMARCC1:SMARCC2 dimer:SMARCD1:SMARCE1:SMARCB1
orthologousEvent	[Reaction:R-CEL-9934028] ARID1A binds SMARCC1:SMARCC2 dimer:SMARCD1:SMARCE1:SMARCB1 - Caenorhabditis elegans [Reaction:R-DME-9934028] ARID1A binds SMARCC1:SMARCC2 dimer:SMARCD1:SMARCE1:SMARCB1 - Drosophila melanogaster [Reaction:R-GGA-9934028] ARID1A binds SMARCC1:SMARCC2 dimer:SMARCD1:SMARCE1:SMARCB1 - Gallus gallus [Reaction:R-SSC-9934028] ARID1A binds SMARCC1:SMARCC2 dimer:SMARCD1:SMARCE1:SMARCB1 - Sus scrofa [Reaction:R-BTA-9934028] ARID1A binds SMARCC1:SMARCC2 dimer:SMARCD1:SMARCE1:SMARCB1 - Bos taurus [Reaction:R-CFA-9934028] ARID1A binds SMARCC1:SMARCC2 dimer:SMARCD1:SMARCE1:SMARCB1 - Canis familiaris [Reaction:R-RNO-9934028] ARID1A binds SMARCC1:SMARCC2 dimer:SMARCD1:SMARCE1:SMARCB1 - Rattus norvegicus [Reaction:R-MMU-9934028] ARID1A binds SMARCC1:SMARCC2 dimer:SMARCD1:SMARCE1:SMARCB1 - Mus musculus
output	[Complex:R-HSA-9934007] SMARCC1:SMARCC2 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1A [nucleoplasm]
precedingEvent	[Reaction:R-HSA-9934026] SMARCE1 and SMARCB1 bind SMARCC1:SMARCC2 dimer:SMARCD1 - Homo sapiens
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2025-03-26
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9938992] Dykhuizen, Emily C, 2025-02-21
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9934028
summation	[Summation:9934000] ARID1A appears to be the most abundant ARID subunit in human...

Referrals

(hasEvent)	[Pathway:R-HSA-9933946] Formation of the embryonic stem cell BAF (esBAF) complex
(precedingEvent)	[Reaction:R-HSA-9934022] DPF2, PHF10 bind SMARCC1:SMARCC2 dimer:SMARD1:ARID1A