Reactome | ARID1A binds SMARCC1:SMARCC2 dimer:SMARCD1:SMARCE1:SMARCB1

ARID1A binds SMARCC1:SMARCC2 dimer:SMARCD1:SMARCE1:SMARCB1

Stable Identifier

R-HSA-9934028

Type

Reaction [binding]

Species

Homo sapiens

Compartment

nucleoplasm

ReviewStatus

5/5

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ARID1A binds SMARCC1:SMARCC2 dimer:SMARCD1:SMARCE1:SMARCB1

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ARID1A appears to be the most abundant ARID subunit in human esBAF complexes, although ARID1B and ARID2 have been identified in low amounts in some human and mouse purifications (Ho, Jothi et al, 2009; Ho, Ronan et al, 2009; Zhang et al, 2014; reviewed in Kadoch and Crabtree, 2015; Innis and Cabot, 2020; Cenik and Shilatifard, 2021).

Literature References

PubMed ID	Title	Journal	Year
25241744	Transcriptional repression by the BRG1-SWI/SNF complex affects the pluripotency of human embryonic stem cells Zhang, X, Li, B, Li, W, Ma, L, Zheng, D, Li, L, Yang, W, Chu, M, Chen, W, Mailman, RB, Zhu, J, Fan, G, Archer, TK, Wang, Y	Stem Cell Reports	2014
32958894	COMPASS and SWI/SNF complexes in development and disease Cenik, BK, Shilatifard, A	Nat Rev Genet	2021
19279218	An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network Ho, L, Jothi, R, Ronan, JL, Cui, K, Zhao, K, Crabtree, GR	Proc Natl Acad Sci U S A	2009
26601204	Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics Kadoch, C, Crabtree, GR	Sci Adv	2015
33143733	GBAF, a small BAF sub-complex with big implications: a systematic review Innis, SM, Cabot, B	Epigenetics Chromatin	2020
19279220	An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency Ho, L, Ronan, JL, Wu, J, Staahl, BT, Chen, L, Kuo, A, Lessard, J, Nesvizhskii, AI, Ranish, J, Crabtree, GR	Proc Natl Acad Sci U S A	2009