Reactome | SMARCC binds SMARCD

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SMARCC binds SMARCD Show undefined attributes

authored	[InstanceEdit:9934146] Rothfels, Karen, 2025-01-06
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9932445] Rothfels, Karen, 2024-12-19
dbId	9932448
displayName	SMARCC binds SMARCD
edited	[InstanceEdit:9934146] Rothfels, Karen, 2025-01-06
eventOf	[Pathway:R-HSA-9933939] Formation of the polybromo-BAF (pBAF) complex - Homo sapiens
followingEvent	[Reaction:R-HSA-9932449] SMARCE1 and SMARCB1 bind SMARCC dimer:SMARCDs - Homo sapiens [Reaction:R-HSA-9932443] BICRA, BICRAL and BRD9 bind SMARCC dimer:SMARCDs - Homo sapiens
input	2 × [DefinedSet:R-HSA-9727493] SMARCC1,2 [nucleoplasm] [DefinedSet:R-HSA-9727492] SMARCD1,2,3 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9932366] A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms [LiteratureReference:9727476] Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes [LiteratureReference:9932374] An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency [LiteratureReference:9933887] Diversity and specialization of mammalian SWI/SNF complexes [LiteratureReference:5225664] Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits
maxDepth	1
modified	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
name	SMARCC binds SMARCD
negativePrecedingEvent	[NegativePrecedingEvent:9934143] Futile Cycle: Formation of neuronal progenitor BAF (npBAF)
orthologousEvent	[Reaction:R-SPO-9932448] SMARCC binds SMARCD - Schizosaccharomyces pombe [Reaction:R-DDI-9932448] SMARCC binds SMARCD - Dictyostelium discoideum [Reaction:R-CEL-9932448] SMARCC binds SMARCD - Caenorhabditis elegans [Reaction:R-DME-9932448] SMARCC binds SMARCD - Drosophila melanogaster [Reaction:R-GGA-9932448] SMARCC binds SMARCD - Gallus gallus [Reaction:R-DRE-9932448] SMARCC binds SMARCD - Danio rerio [Reaction:R-SSC-9932448] SMARCC binds SMARCD - Sus scrofa [Reaction:R-BTA-9932448] SMARCC binds SMARCD - Bos taurus [Reaction:R-CFA-9932448] SMARCC binds SMARCD - Canis familiaris [Reaction:R-RNO-9932448] SMARCC binds SMARCD - Rattus norvegicus [Reaction:R-MMU-9932448] SMARCC binds SMARCD - Mus musculus
output	[Complex:R-HSA-9932417] SMARCC dimer:SMARCDs [nucleoplasm]
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2025-03-26
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9938992] Dykhuizen, Emily C, 2025-02-21
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9932448
summation	[Summation:9932439] SWI/SNF complex assembly begins by the binding of a dimer of...

Referrals

(precedingEvent)	[Reaction:R-HSA-9932443] BICRA, BICRAL and BRD9 bind SMARCC dimer:SMARCDs [Reaction:R-HSA-9932449] SMARCE1 and SMARCB1 bind SMARCC dimer:SMARCDs
(hasEvent)	[Pathway:R-HSA-9933939] Formation of the polybromo-BAF (pBAF) complex

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