Reactome | SMARCE1 and SMARCB1 bind SMARCC1 dimer:SMARCD1

Schema > Reaction > Entries

SMARCE1 and SMARCB1 bind SMARCC1 dimer:SMARCD1 Show undefined attributes

authored	[InstanceEdit:9934146] Rothfels, Karen, 2025-01-06
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9932445] Rothfels, Karen, 2024-12-19
dbId	9932447
displayName	SMARCE1 and SMARCB1 bind SMARCC1 dimer:SMARCD1
edited	[InstanceEdit:9934146] Rothfels, Karen, 2025-01-06
eventOf	[Pathway:R-HSA-9933937] Formation of the canonical BAF (cBAF) complex - Homo sapiens
followingEvent	[Reaction:R-HSA-9932437] ARID1 binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-389261] SMARCB1 [nucleoplasm] [Complex:R-HSA-9932411] SMARCC1 dimer:SMARCD1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-389258] SMARCE1 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9727476] Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes [LiteratureReference:9932362] SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters [LiteratureReference:9932366] A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms [LiteratureReference:9932384] Structure of nucleosome-bound human BAF complex [LiteratureReference:9932381] SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	SMARCE1 and SMARCB1 bind SMARCC1 dimer:SMARCD1
orthologousEvent	[Reaction:R-CEL-9932447] SMARCE1 and SMARCB1 bind SMARCC1 dimer:SMARCD1 - Caenorhabditis elegans [Reaction:R-DME-9932447] SMARCE1 and SMARCB1 bind SMARCC1 dimer:SMARCD1 - Drosophila melanogaster [Reaction:R-GGA-9932447] SMARCE1 and SMARCB1 bind SMARCC1 dimer:SMARCD1 - Gallus gallus [Reaction:R-SSC-9932447] SMARCE1 and SMARCB1 bind SMARCC1 dimer:SMARCD1 - Sus scrofa [Reaction:R-BTA-9932447] SMARCE1 and SMARCB1 bind SMARCC1 dimer:SMARCD1 - Bos taurus [Reaction:R-RNO-9932447] SMARCE1 and SMARCB1 bind SMARCC1 dimer:SMARCD1 - Rattus norvegicus [Reaction:R-MMU-9932447] SMARCE1 and SMARCB1 bind SMARCC1 dimer:SMARCD1 - Mus musculus
output	[Complex:R-HSA-9932416] SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-9932450] SMARCD1 binds SMARCC1 homodimer - Homo sapiens
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2025-03-26
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9938992] Dykhuizen, Emily C, 2025-02-21
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9932447
summation	[Summation:9932436] After formation of the cBAF core trimer consisting of SMARCC...

Referrals

(hasEvent)	[Pathway:R-HSA-9933937] Formation of the canonical BAF (cBAF) complex
(precedingEvent)	[Reaction:R-HSA-9932437] ARID1 binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1