Reactome | p-S-CRY:p-S-PER:CSNK1D,E binds p-S90,Ac-K538-BMAL1:p-2T,3S-CLOCK:target gene

Schema > Reaction > Entries

p-S-CRY:p-S-PER:CSNK1D,E binds p-S90,Ac-K538-BMAL1:p-2T,3S-CLOCK:target gene Show undefined attributes

authored	[InstanceEdit:9922279] May, Bruce, 2024-09-14
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9922276] May, Bruce, 2024-09-21
dbId	9922269
deleted	[Deleted:9938723] Deletion of instance: 400256
displayName	p-S-CRY:p-S-PER:CSNK1D,E binds p-S90,Ac-K538-BMAL1:p-2T,3S-CLOCK:target gene
edited	[InstanceEdit:9922279] May, Bruce, 2024-09-14
eventOf	[Pathway:R-HSA-9931521] The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex - Homo sapiens
followingEvent	[Reaction:R-HSA-9922273] CSNK1D,E phosphorylates CLOCK in p-S-CRY:p-S-PER:CSNK1D,E:p-S90,Ac-538-BMAL:p-2T,3S-CLOCK:target gene - Homo sapiens
inferredFrom	[Reaction:R-MMU-9927987] p-S-Cry:p-S-Per:Csnk1d,e binds p-S97,Ac-K544-Bmal1:p-T451,T461,S440,S441,S446-Clock:Nr1d1 gene - Mus musculus
input	[Complex:R-HSA-9909556] p-S-CRY1:p-S-CRY2:p-S-PER1:p-7S-PER2:p-S-PER3:CSNK1D,E [nucleoplasm] [DefinedSet:R-HSA-9923009] p-S90,Ac-K538-BMAL1:p-T451,T461,S440,S441,S446-CLOCK:target gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9938697] May, Bruce, 2025-02-18
name	p-S-CRY:p-S-PER:CSNK1D,E binds p-S90,Ac-K538-BMAL1:p-2T,3S-CLOCK:target gene
output	[Complex:R-HSA-9922271] p-S-CRY:p-S-PER:CSNK1D,E:p-S90,Ac-K538-BMAL1:p-3S,2T-CLOCK:target gene [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-HSA-9909565] p-S-CRY:p-S-PER:CSNK1D,E complex translocates from the cytosol to the nucleus - Homo sapiens
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2025-03-26
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9938389] Sancar, Aziz, 2025-02-14 [InstanceEdit:9938694] Albrecht, Urs, 2025-02-18
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9922269
summation	[Summation:9931010] The phosphorylated CRY:PER:kinase complex, containing CRY1, ...

Referrals

(replacementInstances)	[Deleted:9938723] Deletion of instance: 400256
(hasEvent)	[Pathway:R-HSA-9931521] The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex
(precedingEvent)	[Reaction:R-HSA-9922273] CSNK1D,E phosphorylates CLOCK in p-S-CRY:p-S-PER:CSNK1D,E:p-S90,Ac-538-BMAL:p-2T,3S-CLOCK:target gene
(inferredTo)	[Reaction:R-MMU-9927987] p-S-Cry:p-S-Per:Csnk1d,e binds p-S97,Ac-K544-Bmal1:p-T451,T461,S440,S441,S446-Clock:Nr1d1 gene

Cite Us!