Reactome | p-S-CRY:p-S-PER:CSNK1D,E complex translocates from the cytosol to the nucleus

Schema > BlackBoxEvent > Entries

p-S-CRY:p-S-PER:CSNK1D,E complex translocates from the cytosol to the nucleus Show undefined attributes

authored	[InstanceEdit:9909554] May, Bruce, 2024-05-14
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:9909554] May, Bruce, 2024-05-14
dbId	9909565
deleted	[Deleted:9938729] Deletion of instance: 549385
displayName	p-S-CRY:p-S-PER:CSNK1D,E complex translocates from the cytosol to the nucleus
edited	[InstanceEdit:9909554] May, Bruce, 2024-05-14
eventOf	[Pathway:R-HSA-9931530] Phosphorylation and nuclear translocation of the CRY:PER:kinase complex - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9932512] FBXL3:CUL1:SKP1:RBX1 ubiquitinylates phosphorylated CRY1,2 - Homo sapiens [Reaction:R-HSA-9932535] FBXL3:CUL1:SKP1:RBX1 binds phosphorylated CRY1,2 - Homo sapiens [Reaction:R-HSA-9922269] p-S-CRY:p-S-PER:CSNK1D,E binds p-S90,Ac-K538-BMAL1:p-2T,3S-CLOCK:target gene - Homo sapiens
inferredFrom	[BlackBoxEvent:R-MMU-9909538] Phosphorylated Cry:Per:Csnk1d,e complex translocates from the cytosol to the nucleus - Mus musculus
input	[Complex:R-HSA-9909377] p-S-CRY1:p-S-CRY2:p-S-PER1:p-7S-PER2:p-S-PER3:CSNK1E,CSNK1D [cytosol]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9939392] May, Bruce, 2025-02-26
name	p-S-CRY:p-S-PER:CSNK1D,E complex translocates from the cytosol to the nucleus
output	[Complex:R-HSA-9909556] p-S-CRY1:p-S-CRY2:p-S-PER1:p-7S-PER2:p-S-PER3:CSNK1D,E [nucleoplasm]
precedingEvent	[Reaction:R-HSA-9909369] CSNK1E,CSNK1D phosphorylate CRY and PER proteins - Homo sapiens
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2025-03-26
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9938389] Sancar, Aziz, 2025-02-14 [InstanceEdit:9938694] Albrecht, Urs, 2025-02-18
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9909565
summation	[Summation:9930076] Cryptochrome (CRY1, CRY2) proteins bind Period (PER1, PER2, ...

Referrals

(replacementInstances)	[Deleted:9938729] Deletion of instance: 549385
(precedingEvent)	[BlackBoxEvent:R-HSA-9932512] FBXL3:CUL1:SKP1:RBX1 ubiquitinylates phosphorylated CRY1,2 [Reaction:R-HSA-9932535] FBXL3:CUL1:SKP1:RBX1 binds phosphorylated CRY1,2 [Reaction:R-HSA-9922269] p-S-CRY:p-S-PER:CSNK1D,E binds p-S90,Ac-K538-BMAL1:p-2T,3S-CLOCK:target gene
(hasEvent)	[Pathway:R-HSA-9931530] Phosphorylation and nuclear translocation of the CRY:PER:kinase complex
(inferredTo)	[BlackBoxEvent:R-MMU-9909538] Phosphorylated Cry:Per:Csnk1d,e complex translocates from the cytosol to the nucleus

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