Reactome | SGC:DAG1:SSPN complex translocates to plasma membrane

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SGC:DAG1:SSPN complex translocates to plasma membrane Show undefined attributes

authored	[InstanceEdit:9926574] Bhat, Hina F, 2024-11-01
category	omitted
compartment	[Compartment:20699] Golgi membrane [Compartment:876] plasma membrane
created	[InstanceEdit:9913331] Rothfels, Karen, 2024-06-13
dbId	9913336
displayName	SGC:DAG1:SSPN complex translocates to plasma membrane
edited	[InstanceEdit:9914712] Rothfels, Karen, 2024-06-26
eventOf	[Pathway:R-HSA-9913351] Formation of the dystrophin-glycoprotein complex (DGC) - Homo sapiens
followingEvent	[Reaction:R-HSA-9913339] Recruitment of dystrophin, dystrobrevin and syntrophin proteins to the DGC - Homo sapiens
input	[Complex:R-HSA-9913295] SGC:DAG1:SSPN complex [Golgi membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9914668] Concomitant deficiency of beta- and gamma-sarcoglycans in 20 alpha-sarcoglycan (adhalin)-deficient patients: immunohistochemical analysis and clinical aspects [LiteratureReference:9914680] Differential requirement for individual sarcoglycans and dystrophin in the assembly and function of the dystrophin-glycoprotein complex [LiteratureReference:9914699] Loss of the sarcoglycan complex and sarcospan leads to muscular dystrophy in beta-sarcoglycan-deficient mice [LiteratureReference:9914690] Identification of functional domains in sarcoglycans essential for their interaction and plasma membrane targeting [LiteratureReference:9913037] Specific assembly pathway of sarcoglycans is dependent on beta- and delta-sarcoglycan [LiteratureReference:9913058] The sarcoglycan complex in skeletal muscle [LiteratureReference:9912926] ABC of multifaceted dystrophin glycoprotein complex (DGC)
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	SGC:DAG1:SSPN complex translocates to plasma membrane
orthologousEvent	[BlackBoxEvent:R-CEL-9913336] SGC:DAG1:SSPN complex translocates to plasma membrane - Caenorhabditis elegans [BlackBoxEvent:R-DME-9913336] SGC:DAG1:SSPN complex translocates to plasma membrane - Drosophila melanogaster [BlackBoxEvent:R-GGA-9913336] SGC:DAG1:SSPN complex translocates to plasma membrane - Gallus gallus [BlackBoxEvent:R-XTR-9913336] SGC:DAG1:SSPN complex translocates to plasma membrane - Xenopus tropicalis [BlackBoxEvent:R-DRE-9913336] SGC:DAG1:SSPN complex translocates to plasma membrane - Danio rerio [BlackBoxEvent:R-SSC-9913336] SGC:DAG1:SSPN complex translocates to plasma membrane - Sus scrofa [BlackBoxEvent:R-BTA-9913336] SGC:DAG1:SSPN complex translocates to plasma membrane - Bos taurus [BlackBoxEvent:R-CFA-9913336] SGC:DAG1:SSPN complex translocates to plasma membrane - Canis familiaris [BlackBoxEvent:R-RNO-9913336] SGC:DAG1:SSPN complex translocates to plasma membrane - Rattus norvegicus [BlackBoxEvent:R-MMU-9913336] SGC:DAG1:SSPN complex translocates to plasma membrane - Mus musculus
output	[Complex:R-HSA-9913286] SGC:DAG1:SSPN complex [plasma membrane]
precedingEvent	[Reaction:R-HSA-9913332] DAG1(30-653), DAG1(654-895) and SSPN bind SGC - Homo sapiens
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2024-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9927641] Bhat, Hina F, 2024-11-08
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9913336
summation	[Summation:9913220] After recruitment of the alpha- and beta-DAG1 components and...

Referrals

(hasEvent)	[Pathway:R-HSA-9913351] Formation of the dystrophin-glycoprotein complex (DGC)
(precedingEvent)	[Reaction:R-HSA-9913339] Recruitment of dystrophin, dystrobrevin and syntrophin proteins to the DGC

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