Reactome | RMTases methylate 16S ribosomal RNA

Schema > Reaction > Entries

RMTases methylate 16S ribosomal RNA Show undefined attributes

authored	[InstanceEdit:9637715] Stephan, Ralf, 2019-02-19
catalystActivity	[CatalystActivity:9639442] rRNA methyltransferase activity of 16S RMTases [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9911521] Stephan, Ralf, 2024-06-01
crossReference	[DatabaseIdentifier:12020761] Mondo:0005113 [DatabaseIdentifier:9911193] RHEA:42773
dbId	9911509
deleted	[Deleted:9911543] Deletion of instance: 9639484
disease	[Disease:3134792] bacterial infectious disease
displayName	RMTases methylate 16S ribosomal RNA
edited	[InstanceEdit:9948470] Stephan, Ralf, 2025-05-21
eventOf	[Pathway:R-HSA-9913143] Antimicrobial resistance - Homo sapiens
input	[EntityWithAccessionedSequence:R-KPN-9638945] Kpn 16S rRNA [cytosol] [SimpleEntity:R-ALL-9639461] S-adenosyl-L-methionine [cytosol]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9639482] RmtF, a new member of the aminoglycoside resistance 16S rRNA N7 G1405 methyltransferase family [LiteratureReference:9913825] Aminoglycoside Resistance: The Emergence of Acquired 16S Ribosomal RNA Methyltransferases [LiteratureReference:9913799] Worldwide disseminated armA aminoglycoside resistance methylase gene is borne by composite transposon Tn1548 [LiteratureReference:9913815] Molecular analysis of NDM-1-producing enterobacterial isolates from Geneva, Switzerland [LiteratureReference:9913812] Exogenously acquired 16S rRNA methyltransferases found in aminoglycoside-resistant pathogenic Gram-negative bacteria: an update [LiteratureReference:9913814] Dissemination of multidrug-resistant Klebsiella pneumoniae clinical isolates with various combinations of carbapenemases (NDM-1 and OXA-72) and 16S rRNA methylases (ArmA, RmtC and RmtF) in Nepal [LiteratureReference:9913842] Coproduction of 16S rRNA methyltransferase RmtD or RmtG with KPC-2 and CTX-M group extended-spectrum ?-lactamases in Klebsiella pneumoniae [LiteratureReference:9913846] Klebsiella pneumoniae sequence type 11 isolate producing RmtG 16S rRNA methyltransferase from a patient in Miami, Florida [LiteratureReference:9913819] Novel 16S rRNA methyltransferase RmtH produced by Klebsiella pneumoniae associated with war-related trauma
maxDepth	1
modified	[InstanceEdit:9948469] Stephan, Ralf, 2025-05-21
name	RMTases methylate 16S ribosomal RNA
output	[EntityWithAccessionedSequence:R-KPN-9639438] 7mG-16S rRNA (Kpn) [cytosol] [SimpleEntity:R-ALL-9639443] S-adenosyl-L-homocysteine [cytosol]
relatedSpecies	[Species:9638647] Klebsiella pneumoniae
releaseDate	2025-06-18
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9911509
summation	[Summation:9639487] Several 16S rRNA (guanine(1405)-N(7))-methyltransferase (16S...

Referrals

(replacementInstances)	[Deleted:9911543] Deletion of instance: 9639484
(hasEvent)	[Pathway:R-HSA-9913143] Antimicrobial resistance