Reactome | MMP14 translocates from the Golgi membrane to the plasma membrane

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MMP14 translocates from the Golgi membrane to the plasma membrane Show undefined attributes

authored	[InstanceEdit:9858813] May, Bruce, 2024-01-14
category	uncertain
compartment	[Compartment:20699] Golgi membrane [Compartment:876] plasma membrane
created	[InstanceEdit:9858809] May, Bruce, 2024-01-14
dbId	9858803
displayName	MMP14 translocates from the Golgi membrane to the plasma membrane
edited	[InstanceEdit:9858813] May, Bruce, 2024-01-14
eventOf	[Pathway:R-HSA-9856530] High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells - Homo sapiens
inferredFrom	[BlackBoxEvent:R-MMU-9858820] Mmp14 translocates from the Golgi membrane to the plasma membrane - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-9858808] MMP14 [Golgi membrane]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9915799] May, Bruce, 2024-07-16
name	MMP14 translocates from the Golgi membrane to the plasma membrane
output	[EntityWithAccessionedSequence:R-HSA-1442472] MMP14 [plasma membrane]
precedingEvent	[Reaction:R-HSA-9855089] PIEZO1 trimer passively transports cations across the plasma membrane according to their electrochemical gradients - Homo sapiens [Reaction:R-HSA-9858800] TRPV4 tetramer:CALM1:Ca2+ transports calcium ions (Ca2+) from the extracellular region to the cytosol - Homo sapiens
regulatedBy	[PositiveRegulation:R-HSA-71542] Positive regulation by 'Ca2+ [cytosol]' [PositiveRegulation:9863406] Positive regulation by 'S1P [extracellular region]'
releaseDate	2024-09-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9915793] Xiao, Rui, 2024-07-16
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9858803
summation	[Summation:9863405] Matrix metalloprotease 14 (MMP14, MT1-MMP) is activated by t...

Referrals

(hasEvent)	[Pathway:R-HSA-9856530] High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
(inferredTo)	[BlackBoxEvent:R-MMU-9858820] Mmp14 translocates from the Golgi membrane to the plasma membrane

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