Reactome | FIRRM binds PLK1

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FIRRM binds PLK1 Show undefined attributes

authored	[InstanceEdit:9851977] Orlic-Milacic, Marija, 2023-11-02
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9851950] Orlic-Milacic, Marija, 2023-11-02
dbId	9851946
displayName	FIRRM binds PLK1
edited	[InstanceEdit:9863557] Orlic-Milacic, Marija, 2024-03-01
eventOf	[Pathway:R-HSA-2500257] Resolution of Sister Chromatid Cohesion - Homo sapiens
followingEvent	[Reaction:R-HSA-9851972] PLK1 phosphorylates FIRRM at S43 - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9851948] FIRRM [cytosol] [EntityWithAccessionedSequence:R-HSA-3000318] p-T210-PLK1 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9851945] Feedback control of PLK1 by Apolo1 ensures accurate chromosome segregation
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	FIRRM binds PLK1
negativePrecedingEvent	[NegativePrecedingEvent:9910666] Futile Cycle: PLK1 phosphorylates FIRMM at S744
orthologousEvent	[Reaction:R-GGA-9851946] FIRRM binds PLK1 - Gallus gallus [Reaction:R-DRE-9851946] FIRRM binds PLK1 - Danio rerio [Reaction:R-SSC-9851946] FIRRM binds PLK1 - Sus scrofa [Reaction:R-BTA-9851946] FIRRM binds PLK1 - Bos taurus [Reaction:R-CFA-9851946] FIRRM binds PLK1 - Canis familiaris [Reaction:R-RNO-9851946] FIRRM binds PLK1 - Rattus norvegicus [Reaction:R-MMU-9851946] FIRRM binds PLK1 - Mus musculus
output	[Complex:R-HSA-9851951] FIRRM:p-T210-PLK1 [cytosol]
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2024-03-27
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9863560] Liu, Xing, 2024-03-01 [InstanceEdit:9863558] Yao, Xuebiao, 2024-03-01 [InstanceEdit:9909004] Orthwein, Alexandre, 2024-04-26
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9851946
summation	[Summation:9851969] FIRRM (also known as Apolo1, FINGL1-interacting regulator of...
updateTrackers	[UpdateTracker:9911089] Update Tracker - [Reaction:9851946] FIRRM binds PLK1 - v89:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9911089] Update Tracker - [Reaction:9851946] FIRRM binds PLK1 - v89:[modifyText]
(hasEvent)	[Pathway:R-HSA-2500257] Resolution of Sister Chromatid Cohesion
(precedingEvent)	[Reaction:R-HSA-9851972] PLK1 phosphorylates FIRRM at S43

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