Reactome | ligand-bound ALK dimer [plasma membrane]

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ligand-bound ALK dimer [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:9700102] protein tyrosine kinase activity of ligand-bound ALK dimer [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-9700592] ALK dimer:ligand:type I ALK binding TKI [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9700662] Liganded-ALK dimer binds type I ALK-binding TKIs - Homo sapiens [Reaction:R-HSA-201521] ALK autophosphorylation - Homo sapiens
created	[InstanceEdit:9850907] Rothfels, Karen, 2023-10-12
dbId	9850908
displayName	ligand-bound ALK dimer [plasma membrane]
hasCandidate	[Complex:R-HSA-201496] PTN:ALK dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9699997] MDK:ALK dimer [plasma membrane] - Homo sapiens
hasMember	[Complex:R-HSA-9842608] ALK dimer:ALKAL2:(ALKAL1) [plasma membrane] - Homo sapiens
inDisease	false
inferredTo	[CandidateSet:R-MMU-9850908] ligand-bound ALK dimer [plasma membrane] - Mus musculus [CandidateSet:R-RNO-9850908] ligand-bound ALK dimer [plasma membrane] - Rattus norvegicus [CandidateSet:R-CFA-9850908] ligand-bound ALK dimer [plasma membrane] - Canis familiaris [CandidateSet:R-BTA-9850908] ligand-bound ALK dimer [plasma membrane] - Bos taurus [CandidateSet:R-SSC-9850908] ligand-bound ALK dimer [plasma membrane] - Sus scrofa [CandidateSet:R-DRE-9850908] ligand-bound ALK dimer [plasma membrane] - Danio rerio [CandidateSet:R-XTR-9850908] ligand-bound ALK dimer [plasma membrane] - Xenopus tropicalis [CandidateSet:R-GGA-9850908] ligand-bound ALK dimer [plasma membrane] - Gallus gallus
maxDepth	5
modified	[InstanceEdit:9851210] Rothfels, Karen, 2023-10-14
name	ligand-bound ALK dimer
schemaClass	CandidateSet
species	[Species:48887] Homo sapiens
stId	R-HSA-9850908

Referrals

(input)	[Reaction:R-HSA-9700662] Liganded-ALK dimer binds type I ALK-binding TKIs [Reaction:R-HSA-201521] ALK autophosphorylation
(hasComponent)	[Complex:R-HSA-9700592] ALK dimer:ligand:type I ALK binding TKI [plasma membrane]
(physicalEntity)	[CatalystActivity:9700102] protein tyrosine kinase activity of ligand-bound ALK dimer [plasma membrane]

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