Reactome | SMAD1:SMAD4 trimer binds ZNF423

Schema > Reaction > Entries

authored	[InstanceEdit:9844988] Orlic-Milacic, Marija, 2023-09-25
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9844426] Orlic-Milacic, Marija, 2023-09-16
dbId	9844425
displayName	SMAD1:SMAD4 trimer binds ZNF423
edited	[InstanceEdit:9855181] Orlic-Milacic, Marija, 2023-11-29
eventOf	[Pathway:R-HSA-9844594] Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 - Homo sapiens
inferredFrom	[Reaction:R-MMU-9844497] Smad1:Smad4 trimer binds Znf423 - Mus musculus
input	[Complex:R-HSA-206654] p-2S-SMAD1:p-2S-SMAD1:SMAD4 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-3222318] ZNF423 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9855221] Orlic-Milacic, Marija, 2023-11-29
name	SMAD1:SMAD4 trimer binds ZNF423
output	[Complex:R-HSA-9844431] ZNF423:p-2S-SMAD1:p-2S-SMAD1:SMAD4 [nucleoplasm]
previousReviewStatus	[ReviewStatus:9821383] three stars
regulatedBy	[PositiveRegulation:9844432] Positive regulation by 'BMP7 dimer [extracellular region]'
releaseDate	2024-03-27
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9854531] Chun, Tae-Hwa, 2023-11-29
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9844425
summation	[Summation:9844498] Based on studies in mice, bone morphogenic protein BMP7, kno...

(hasEvent)	[Pathway:R-HSA-9844594] Transcriptional regulation of brown and beige adipocyte differentiation by EBF2
(inferredTo)	[Reaction:R-MMU-9844497] Smad1:Smad4 trimer binds Znf423

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