TGFBR3 binding to FGF2

Stable Identifier
R-HSA-9839379
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
3/5
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TGFBR3 binding to FGF2
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TGFBR3 (Betaglycan) bind bFGF via its heparan sulphate chains(GAGs) and form ternary complexes with FGFs and FGF receptors in neuronal development (Andrea et al. 1992 and Knelson et al, 2013)
Literature References
PubMed ID Title Journal Year
1556106 Binding of two growth factor families to separate domains of the proteoglycan betaglycan

DeFalcis, D, Noda, M, Massagué, J, Andres, JL

J Biol Chem 1992
24216509 Type III TGF-β receptor promotes FGF2-mediated neuronal differentiation in neuroblastoma

Mythreye, K, Blobe, GC, Armstrong, MB, Gaviglio, AL, Tewari, AK, Knelson, EH

J Clin Invest 2013
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Authored
Tiwari, K  (2023-07-25)
Created
Tiwari, K  (2023-07-05)
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