Reactome | Ubiquitination of STAT2

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Ubiquitination of STAT2 Show undefined attributes

authored	[InstanceEdit:9837377] Stephan, Ralf, 2023-06-14
catalystActivity	[CatalystActivity:9833156] ubiquitin-protein transferase activity of NS1:Cul5-SCF [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9833157] Stephan, Ralf, 2023-04-13
crossReference	[DatabaseIdentifier:12020771] Mondo:0001577
dbId	9833155
disease	[Disease:9833927] respiratory syncytial virus infectious disease
displayName	Ubiquitination of STAT2
edited	[InstanceEdit:9852986] Stephan, Ralf, 2023-11-09
eventOf	[Pathway:R-HSA-9833109] Evasion by RSV of host interferon responses - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-882029] STAT2 [cytosol] 4 × [DefinedSet:R-HSA-113595] Ub [cytosol]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9833113] Respiratory syncytial virus NS1 protein degrades STAT2 by using the Elongin-Cullin E3 ligase
maxDepth	1
modified	[InstanceEdit:9852992] Stephan, Ralf, 2023-11-09
name	Ubiquitination of STAT2
output	[Complex:R-HSA-9833154] multiubiquitinated STAT2 [cytosol]
precedingEvent	[Reaction:R-HSA-9833107] Association of NS1 (1C) with Cul5 and SCF - Homo sapiens
relatedSpecies	[Species:9717528] Human respiratory syncytial virus A
releaseDate	2023-12-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9852848] Bergeron, Harrison Christopher, 2023-11-03
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9833155
summation	[Summation:9833158] Human signal transducer and activator of transcription 2 (ST...

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[Pathway:R-HSA-9833109] Evasion by RSV of host interferon responses

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