Reactome | EYA1, PAX2, and HOX11 paralog bind the GDNF gene

Schema > Reaction > Entries

authored	[InstanceEdit:9830957] May, Bruce, 2023-03-15
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9830919] May, Bruce, 2023-03-17
dbId	9830969
displayName	EYA1, PAX2, and HOX11 paralog bind the GDNF gene
edited	[InstanceEdit:9830957] May, Bruce, 2023-03-15
eventOf	[Pathway:R-HSA-9830674] Formation of the ureteric bud - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9830765] Expression of GDNF in metanephric mesenchyme - Homo sapiens
inferredFrom	[Reaction:R-MMU-9830938] Eya1, Pax2, and Hox11 paralog bind the Gdnf gene - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-5683625] EYA1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9830759] GDNF gene [nucleoplasm] [DefinedSet:R-HSA-9830925] HOX11 paralog [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9761175] PAX2 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9851767] May, Bruce, 2023-10-31
name	EYA1, PAX2, and HOX11 paralog bind the GDNF gene
output	[Complex:R-HSA-9830937] EYA1:PAX2:HOX11 paralog:GDNF gene [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-HSA-9830945] Expression of EYA1 in metanephric mesenchyme - Homo sapiens
releaseDate	2023-12-06
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9830969
summation	[Summation:9831840] HOXA11 (or HOXC11 or HOXD11) , EYA1, and PAX2 physically int...

(precedingEvent)	[BlackBoxEvent:R-HSA-9830765] Expression of GDNF in metanephric mesenchyme
(hasEvent)	[Pathway:R-HSA-9830674] Formation of the ureteric bud
(inferredTo)	[Reaction:R-MMU-9830938] Eya1, Pax2, and Hox11 paralog bind the Gdnf gene

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