Reactome | Expression of GDNF in metanephric mesenchyme

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Expression of GDNF in metanephric mesenchyme Show undefined attributes

authored	[InstanceEdit:9830701] May, Bruce, 2023-03-13
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:984] extracellular region
created	[InstanceEdit:9830747] May, Bruce, 2023-03-14
dbId	9830765
displayName	Expression of GDNF in metanephric mesenchyme
edited	[InstanceEdit:9830701] May, Bruce, 2023-03-13
eventOf	[Pathway:R-HSA-9830674] Formation of the ureteric bud - Homo sapiens
inferredFrom	[BlackBoxEvent:R-MMU-9830744] Expression of Gdnf in metanephric mesenchyme - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-9830759] GDNF gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9851767] May, Bruce, 2023-10-31
name	Expression of GDNF in metanephric mesenchyme
output	[EntityWithAccessionedSequence:R-HSA-375061] GDNF [extracellular region]
precedingEvent	[BlackBoxEvent:R-HSA-9830762] Expression of WNT11 in the nephric duct - Homo sapiens [Reaction:R-HSA-9830969] EYA1, PAX2, and HOX11 paralog bind the GDNF gene - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:9830745] Positive gene expression regulation by 'N4GlycoAsn-PalmS WNT11 [extracellular region]' [PositiveGeneExpressionRegulation:9830950] Positive gene expression regulation by 'NPNT:ITGA8:ITGB1 [plasma membrane]' [PositiveGeneExpressionRegulation:9830954] Positive gene expression regulation by 'EYA1:PAX2:HOX11 paralog:GDNF gene [nucleoplasm]' [NegativeGeneExpressionRegulation:9792556] Negative gene expression regulation by 'FOXC1 [nucleoplasm]' [NegativeGeneExpressionRegulation:9792545] Negative gene expression regulation by 'FOXC2 [nucleoplasm]' [NegativeGeneExpressionRegulation:9831058] Negative gene expression regulation by 'ROBO2:SLIT2 [plasma membrane]'
releaseDate	2023-12-06
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9830765
summation	[Summation:9831858] Glial cell line-derived neurotrophic factor (GDNF) is expres...

Referrals

(hasEvent)	[Pathway:R-HSA-9830674] Formation of the ureteric bud
(inferredTo)	[BlackBoxEvent:R-MMU-9830744] Expression of Gdnf in metanephric mesenchyme

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