Reactome | F0 gets N-glycosylated

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F0 gets N-glycosylated Show undefined attributes

authored	[InstanceEdit:9828804] Stephan, Ralf, 2023-02-18
category	uncertain
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:6791047] endoplasmic reticulum-Golgi intermediate compartment membrane
created	[InstanceEdit:9829041] Stephan, Ralf, 2023-02-22
crossReference	[DatabaseIdentifier:12020771] Mondo:0001577
dbId	9829060
disease	[Disease:9833927] respiratory syncytial virus infectious disease
displayName	F0 gets N-glycosylated
edited	[InstanceEdit:9852992] Stephan, Ralf, 2023-11-09
eventOf	[Pathway:R-HSA-9828806] Maturation of hRSV A proteins - Homo sapiens
followingEvent	[Reaction:R-HSA-9829047] F0 is palmitoylated - Homo sapiens
input	[EntityWithAccessionedSequence:R-RSY-9829032] F0 [endoplasmic reticulum membrane]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9829048] Respiratory syncytial virus fusion glycoprotein: nucleotide sequence of mRNA, identification of cleavage activation site and amino acid sequence of N-terminus of F1 subunit [LiteratureReference:9829044] Role of oligosaccharides in the structure and function of respiratory syncytial virus glycoproteins [LiteratureReference:9829034] Intracellular processing of the human respiratory syncytial virus fusion glycoprotein: amino acid substitutions affecting folding, transport and cleavage [LiteratureReference:9829042] Evidence that maturation of the N-linked glycans of the respiratory syncytial virus (RSV) glycoproteins is required for virus-mediated cell fusion: The effect of alpha-mannosidase inhibitors on RSV infectivity [LiteratureReference:9829050] Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers [LiteratureReference:9829059] N-glycans of F protein differentially affect fusion activity of human respiratory syncytial virus
maxDepth	1
modified	[InstanceEdit:9852993] Stephan, Ralf, 2023-11-09
name	F0 gets N-glycosylated
output	[EntityWithAccessionedSequence:R-RSY-9829051] N-glycan-F0 [endoplasmic reticulum-Golgi intermediate compartment membrane]
precedingEvent	[BlackBoxEvent:R-HSA-9829030] Nascent F signal peptide is cleaved at ER membrane - Homo sapiens
relatedSpecies	[Species:9717528] Human respiratory syncytial virus A
releaseDate	2023-12-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9852848] Bergeron, Harrison Christopher, 2023-11-03
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9829060
summation	[Summation:9829058] Prepro-fusion protein F0 of human respiratory syncytial viru...

Referrals

(hasEvent)	[Pathway:R-HSA-9828806] Maturation of hRSV A proteins
(precedingEvent)	[Reaction:R-HSA-9829047] F0 is palmitoylated