Reactome | ZnT5 transports zinc into the golgi apparatus

Schema > Reaction > Entries

ZnT5 transports zinc into the golgi apparatus Show undefined attributes

authored	[InstanceEdit:9817556] D'Eustachio, Peter, 2022-09-23
catalystActivity	[CatalystActivity:437132] zinc ion transmembrane transporter activity of SLC30A5 dimer [Golgi membrane]
catalystActivityReference	[CatalystActivityReference:9817566] zinc ion transmembrane transporter activity of SLC30A5 dimer [Golgi membrane] Cloning and characterization of a novel mammalian zinc transporter, zinc transporter 5, abundantly expressed in pancreatic beta cells
category	transition
compartment	[Compartment:20699] Golgi membrane
created	[InstanceEdit:9820568] D'Eustachio, Peter, 2022-11-09
crossReference	[DatabaseIdentifier:12667915] RHEA:29351
dbId	9820566
deleted	[Deleted:9820570] Deletion of instance: 437129
displayName	ZnT5 transports zinc into the golgi apparatus
edited	[InstanceEdit:9817556] D'Eustachio, Peter, 2022-09-23
eventOf	[Pathway:R-HSA-264876] Insulin processing - Homo sapiens [Pathway:R-HSA-435368] Zinc efflux and compartmentalization by the SLC30 family - Homo sapiens
followingEvent	[Reaction:R-HSA-264976] Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:6792028] zinc ion import into Golgi lumen
input	[SimpleEntity:R-ALL-29426] Zn2+ [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9817563] Zinc and zinc transporter regulation in pancreatic islets and the potential role of zinc in islet transplantation [LiteratureReference:437091] Cloning and characterization of a novel mammalian zinc transporter, zinc transporter 5, abundantly expressed in pancreatic beta cells [LiteratureReference:9817567] Zinc transporters and their functional integration in mammalian cells
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	ZnT5 transports zinc into the golgi apparatus
orthologousEvent	[Reaction:R-SCE-9820566] ZnT5 transports zinc into the golgi apparatus - Saccharomyces cerevisiae [Reaction:R-SPO-9820566] ZnT5 transports zinc into the golgi apparatus - Schizosaccharomyces pombe [Reaction:R-DDI-9820566] ZnT5 transports zinc into the golgi apparatus - Dictyostelium discoideum [Reaction:R-CEL-9820566] ZnT5 transports zinc into the golgi apparatus - Caenorhabditis elegans [Reaction:R-GGA-9820566] ZnT5 transports zinc into the golgi apparatus - Gallus gallus [Reaction:R-XTR-9820566] ZnT5 transports zinc into the golgi apparatus - Xenopus tropicalis [Reaction:R-DRE-9820566] ZnT5 transports zinc into the golgi apparatus - Danio rerio [Reaction:R-SSC-9820566] ZnT5 transports zinc into the golgi apparatus - Sus scrofa [Reaction:R-BTA-9820566] ZnT5 transports zinc into the golgi apparatus - Bos taurus [Reaction:R-CFA-9820566] ZnT5 transports zinc into the golgi apparatus - Canis familiaris [Reaction:R-RNO-9820566] ZnT5 transports zinc into the golgi apparatus - Rattus norvegicus [Reaction:R-MMU-9820566] ZnT5 transports zinc into the golgi apparatus - Mus musculus
output	[SimpleEntity:R-ALL-216667] Zn2+ [Golgi lumen]
precedingEvent	[Reaction:R-HSA-442422] SLC39A1-4 transports Zn2+ from extracellular region to cytosol - Homo sapiens [Reaction:R-HSA-442317] ZIP6 and ZIP14 mediate zinc influx into cells - Homo sapiens [Reaction:R-HSA-442393] ZIP7 mediates zinc efflux from the endoplasmic reticulum - Homo sapiens [Reaction:R-HSA-442387] ZIP8 mediates zinc influx into cells - Homo sapiens [Reaction:R-HSA-442345] hZIP10 mediates zinc influx into cells - Homo sapiens [Reaction:R-HSA-442405] hZIP5 mediates zinc uptake by cells - Homo sapiens
releaseDate	2022-12-07
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9820567] Hill, David P, 2022-11-09
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9820566
summation	[Summation:437142] Dimeric ZnT5/SLC30A5 mediates the transport of cytosolic Zn2...

Referrals

(replacementInstances)	[Deleted:9820570] Deletion of instance: 437129
(precedingEvent)	[Reaction:R-HSA-264976] Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium
(hasEvent)	[Pathway:R-HSA-264876] Insulin processing [Pathway:R-HSA-435368] Zinc efflux and compartmentalization by the SLC30 family

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