Reactome | Expression of ZSCAN4 in the embryo

Schema > BlackBoxEvent > Entries

Expression of ZSCAN4 in the embryo Show undefined attributes

authored	[InstanceEdit:9818493] May, Bruce, 2022-10-17
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9818488] May, Bruce, 2022-10-18
dbId	9818523
displayName	Expression of ZSCAN4 in the embryo
edited	[InstanceEdit:9818493] May, Bruce, 2022-10-17
eventOf	[Pathway:R-HSA-9819196] Zygotic genome activation (ZGA) - Homo sapiens
inferredFrom	[BlackBoxEvent:R-MMU-9820700] Expression of Zscan4 in the embryo - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-9816413] ZSCAN4 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:9818480] Translatome and transcriptome co-profiling reveals a role of TPRXs in human zygotic genome activation [LiteratureReference:9816444] Conserved roles of mouse DUX and human DUX4 in activating cleavage-stage genes and MERVL/HERVL retrotransposons [LiteratureReference:9820754] Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos [LiteratureReference:9820756] Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells
maxDepth	1
modified	[InstanceEdit:9841067] May, Bruce, 2023-08-08
name	Expression of ZSCAN4 in the embryo
output	[EntityWithAccessionedSequence:R-HSA-9816447] ZSCAN4 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-9816396] DUX4, TPRXL, TPRX1, TPRX2, EP300, and CREBBP bind the ZSCAN4 gene - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:9818502] Positive gene expression regulation by 'DUX4:TPRXL:TPRX1:TPRX2:EP300:CREBBP:ZSCAN4 gene [nucleoplasm]'
regulationReference	[RegulationReference:9820715] Positive gene expression regulation by 'DUX4:TPRXL:TPRX1:TPRX2:EP300:CREBBP:ZSCAN4 gene [nucleoplasm]' Conserved roles of mouse DUX and human DUX4 in activating cleavage-stage genes and MERVL/HERVL retrotransposons
releaseDate	2023-09-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9841065] Xie, Wei, 2023-08-08
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9818523
summation	[Summation:9820744] The ZSCAN4 gene, the single human homolog of the Zscan4 gene...

Referrals

(hasEvent)	[Pathway:R-HSA-9819196] Zygotic genome activation (ZGA)
(inferredTo)	[BlackBoxEvent:R-MMU-9820700] Expression of Zscan4 in the embryo