Reactome | K63,M1polyUb-RIPK1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

K63,M1polyUb-RIPK1 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9817409] TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] - Homo sapiens
created	[InstanceEdit:9793675] Shamovsky, Veronica, 2022-06-23
dbId	9793681
displayName	K63,M1polyUb-RIPK1 [cytosol]
endCoordinate	671
hasModifiedResidue	[GroupModifiedResidue:3080599] ubiquitinylated lysine (K63-polyubiquitin [cytosol]) at 377 [GroupModifiedResidue:9793662] ubiquitinylated lysine (M1polyUb [cytosol]) at 627
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-9793681] K63,M1polyUb-RIPK1 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-9793681] Ripk1 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-9793681] RIPK1 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-9793681] RIPK1 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-9793681] RIPK1 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-9793681] ripk1l [cytosol] - Danio rerio
literatureReference	[LiteratureReference:451562] Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
maxDepth	1
modified	[InstanceEdit:9816085] Shamovsky, Veronica, 2022-08-31
name	K63,M1polyUb-RIPK1 K63polyUb, M1polyUb-RIPK1 K63-, M1-linked polyUb - RIP1
referenceEntity	[ReferenceGeneProduct:uniprot:Q13546] UniProt:Q13546 RIPK1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9793681
startCoordinate	1
updateTrackers	[UpdateTracker:9905153] Update Tracker - [EntityWithAccessionedSequence:9793681] K63,M1polyUb-RIPK1 [cytosol] - v83:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9905153] Update Tracker - [EntityWithAccessionedSequence:9793681] K63,M1polyUb-RIPK1 [cytosol] - v83:[modifyName]
(hasComponent)	[Complex:R-HSA-9817409] TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] [Complex:R-HSA-9793688] TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] [Complex:R-HSA-9817363] TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane]