Reactome | ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol]

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ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9766685] SESN1,2:ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9766687] SESN1,SESN1 bind SQSTM1 and KEAP1 - Homo sapiens
created	[InstanceEdit:9766541] Rothfels, Karen, 2022-02-22
dbId	9766542
displayName	ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol]
hasComponent	[Complex:R-HSA-8932333] KEAP1:NEDD8-CUL3:RBX1 [cytosol] [Complex:R-HSA-9766539] ub-K420 p-S349 SQSTM1 oligomer [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-9766542] ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] - Mus musculus [Complex:R-RNO-9766542] ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] - Rattus norvegicus [Complex:R-CFA-9766542] ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] - Canis familiaris [Complex:R-BTA-9766542] ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] - Bos taurus [Complex:R-SSC-9766542] ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] - Sus scrofa [Complex:R-DRE-9766542] ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] - Danio rerio [Complex:R-XTR-9766542] ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] - Xenopus tropicalis [Complex:R-GGA-9766542] ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] - Gallus gallus [Complex:R-DME-9766542] ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] - Drosophila melanogaster [Complex:R-CEL-9766542] ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] - Caenorhabditis elegans [Complex:R-DDI-9766542] ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] - Dictyostelium discoideum [Complex:R-PFA-9766542] ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] - Plasmodium falciparum
isChimeric	false
maxDepth	3
modified	[InstanceEdit:9766668] Rothfels, Karen, 2022-02-23
name	ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1
negativelyRegulates	[NegativeRegulation:9759128] Negative regulation by 'ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol]'
producedByEvent	[Reaction:R-HSA-9759172] KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9766542

Referrals

(regulator)	[NegativeRegulation:9759128] Negative regulation by 'ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol]'
(output)	[Reaction:R-HSA-9759172] KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer
(input)	[Reaction:R-HSA-9766687] SESN1,SESN1 bind SQSTM1 and KEAP1
(hasComponent)	[Complex:R-HSA-9766685] SESN1,2:ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol]

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