Reactome | RBX1-CUL5-EloB/C-SOCS [cytosol]

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RBX1-CUL5-EloB/C-SOCS [cytosol] Show undefined attributes

candidateOf	[CandidateSet:R-HSA-976075] E3 ligases in proteasomal degradation [cytosol] - Homo sapiens
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:976088] Garapati, P V, 2010-10-11
dbId	976147
displayName	RBX1-CUL5-EloB/C-SOCS [cytosol]
hasComponent	[Complex:R-HSA-180596] Cul5-SCF complex [cytosol] [DefinedSet:R-HSA-877267] SOCS-1 and SOCS-3 [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-976147] RBX1-CUL5-EloB/C-SOCS [cytosol] - Mus musculus [Complex:R-RNO-976147] RBX1-CUL5-EloB/C-SOCS [cytosol] - Rattus norvegicus [Complex:R-CFA-976147] RBX1-CUL5-EloB/C-SOCS [cytosol] - Canis familiaris [Complex:R-BTA-976147] RBX1-CUL5-EloB/C-SOCS [cytosol] - Bos taurus [Complex:R-SSC-976147] RBX1-CUL5-EloB/C-SOCS [cytosol] - Sus scrofa [Complex:R-DRE-976147] RBX1-CUL5-EloB/C-SOCS [cytosol] - Danio rerio [Complex:R-XTR-976147] RBX1-CUL5-EloB/C-SOCS [cytosol] - Xenopus tropicalis [Complex:R-GGA-976147] RBX1-CUL5-EloB/C-SOCS [cytosol] - Gallus gallus [Complex:R-DME-976147] RBX1-CUL5-EloB/C-SOCS [cytosol] - Drosophila melanogaster [Complex:R-CEL-976147] RBX1-CUL5-EloB/C-SOCS [cytosol] - Caenorhabditis elegans
isChimeric	false
literatureReference	[LiteratureReference:976158] The suppressors of cytokine signalling E3 ligases behave as tumour suppressors [LiteratureReference:976092] The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families [LiteratureReference:976135] Degradation of phosphorylated p53 by viral protein-ECS E3 ligase complex
maxDepth	3
name	RBX1-CUL5-EloB/C-SOCS ECS (Elongin-Cullin-SOCS) E3 ligase
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-976147

Referrals

(hasCandidate)

[CandidateSet:R-HSA-976075] E3 ligases in proteasomal degradation [cytosol]

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