Reactome | RBX1-CUL5-EloB/C-SOCS [cytosol]

Stable Identifier

R-HSA-976147

Type

Complex

Species

Homo sapiens

Compartment

cytosol

Synonyms

ECS (Elongin-Cullin-SOCS) E3 ligase

Locations in the PathwayBrowser

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Literature References

PubMed ID	Title	Journal	Year
19649319	Degradation of phosphorylated p53 by viral protein-ECS E3 ligase complex Isomura, H, Kamura, T, Tsurumi, T, Nakayama, S, Sato, Y, Kudoh, A, Shirata, N, Nishiyama, Y, Iwahori, S, Murata, T	PLoS Pathog	2009
9869640	The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families Kamura, T, Liu, L, Haque, D, Sato, S, Kaelin WG, Jr, Conaway, JW, Conaway, RC	Genes Dev	1998
18481982	The suppressors of cytokine signalling E3 ligases behave as tumour suppressors Hookham, MB, Johnston, JA, Elliott, J	Biochem Soc Trans	2008

Participants

components

Participates

as a candidate of

Inferred To

RBX1-CUL5-EloB/C-SOCS [cytosol] (Bos taurus)

RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)

RBX1-CUL5-EloB/C-SOCS [cytosol] (Mus musculus)

RBX1-CUL5-EloB/C-SOCS [cytosol] (Sus scrofa)