Reactome | STUB1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

STUB1 [cytosol] Show undefined attributes

candidateOf	[CandidateSet:R-HSA-976075] E3 ligases in proteasomal degradation [cytosol] - Homo sapiens
catalystActivities	[CatalystActivity:1918091] ubiquitin-protein transferase activity of STUB1 [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9688809] STUB1:STUB1 [cytosol] - Homo sapiens [Complex:R-HSA-9688809] STUB1:STUB1 [cytosol] - Homo sapiens [Complex:R-HSA-9009311] RUNX2:STUB1 [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9009309] RUNX2 binds STUB1 - Homo sapiens [Reaction:R-HSA-2187375] SMAD3 binds STUB1 (CHIP) - Homo sapiens
created	[InstanceEdit:976001] Garapati, P V, 2010-10-11
dbId	975970
displayName	STUB1 [cytosol]
endCoordinate	303
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-975970] Stub1 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-975970] STUB1 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-975970] STUB1 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-975970] STUB1 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-975970] STUB1 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-XTR-975970] stub1 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-975970] STUB1 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-975970] STUB1 [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-975970] chn-1 [cytosol] - Caenorhabditis elegans [GenomeEncodedEntity:R-DDI-975970] Ghost homologue of STUB1 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-PFA-975970] STUB1 [cytosol] - Plasmodium falciparum
maxDepth	1
memberOf	[DefinedSet:R-HSA-6807286] NEDD4,STUB1,WWP2 and XIAP [cytosol] - Homo sapiens
modified	[InstanceEdit:3448660] Wu, G, 2013-05-16
name	STUB1 E3 ubiquitin-protein ligase CHIP CHIP_HUMAN
producedByEvent	[Reaction:R-HSA-9009308] STUB1 polyubiquitinates RUNX2 - Homo sapiens [Reaction:R-HSA-2187368] STUB1 (CHIP) ubiquitinates SMAD3 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q9UNE7] UniProt:Q9UNE7 STUB1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-975970
startCoordinate	1

Referrals

(output)	[Reaction:R-HSA-9009308] STUB1 polyubiquitinates RUNX2 [Reaction:R-HSA-2187368] STUB1 (CHIP) ubiquitinates SMAD3
(activeUnit)	[CatalystActivity:9009313] ubiquitin protein ligase activity of RUNX2:STUB1 [cytosol] [CatalystActivity:2187377] ubiquitin-protein transferase activity of SMAD3:STUB1 [cytosol]
(hasComponent)	[Complex:R-HSA-9009311] RUNX2:STUB1 [cytosol] [Complex:R-HSA-9688809] STUB1:STUB1 [cytosol] [Complex:R-HSA-2187365] SMAD3:STUB1 [cytosol]
(input)	[Reaction:R-HSA-9009309] RUNX2 binds STUB1 [Reaction:R-HSA-2187375] SMAD3 binds STUB1 (CHIP)
(physicalEntity)	[CatalystActivity:1918091] ubiquitin-protein transferase activity of STUB1 [cytosol]
(hasMember)	[DefinedSet:R-HSA-6807286] NEDD4,STUB1,WWP2 and XIAP [cytosol]
(hasCandidate)	[CandidateSet:R-HSA-976075] E3 ligases in proteasomal degradation [cytosol]