Reactome | NQO1 gene:p-AcK-NFE2L2:CHD6:MAFK [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9759115] Rothfels, Karen, 2021-11-29
dbId	9759114
displayName	NQO1 gene:p-AcK-NFE2L2:CHD6:MAFK [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-9944065] CHD6 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-1008242] MAFK [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9759080] NQO1 gene [nucleoplasm] [Complex:R-HSA-9760062] p-AcK-NFE2L2:CREBBP, EP300 [nucleoplasm]
inDisease	false
isChimeric	false
literatureReference	[LiteratureReference:9758970] An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
maxDepth	4
modified	[InstanceEdit:9944241] Rothfels, Karen, 2025-04-03
name	NQO1 gene:p-AcK-NFE2L2:CHD6:MAFK
positivelyRegulates	[PositiveGeneExpressionRegulation:9759185] Positive gene expression regulation by 'NQO1 gene:p-AcK-NFE2L2:CHD6:MAFK [nucleoplasm]'
producedByEvent	[Reaction:R-HSA-9759141] AcK-NFE2L2, CHD6 and MAFK bind NQO1 gene - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9759114
updateTrackers	[UpdateTracker:9953922] Update Tracker - [Complex:9759114] NQO1 gene:p-AcK-NFE2L2:CHD6:MAFK [nucleoplasm] - v93:[modifyName, removeHasComponent]

(updatedInstance)	[UpdateTracker:9953922] Update Tracker - [Complex:9759114] NQO1 gene:p-AcK-NFE2L2:CHD6:MAFK [nucleoplasm] - v93:[modifyName, removeHasComponent]
(output)	[Reaction:R-HSA-9759141] AcK-NFE2L2, CHD6 and MAFK bind NQO1 gene
(regulator)	[PositiveGeneExpressionRegulation:9759185] Positive gene expression regulation by 'NQO1 gene:p-AcK-NFE2L2:CHD6:MAFK [nucleoplasm]'

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