Reactome | Positive gene expression regulation by 'NQO1 gene:p-AcK-NFE2L2:CHD6:MAFK [nucleoplasm]'

Schema > PositiveGeneExpressionRegulation > Entries

activeUnit	[EntityWithAccessionedSequence:R-HSA-1008242] MAFK [nucleoplasm] - Homo sapiens [CandidateSet:R-HSA-9708562] p-NFE2L2 [nucleoplasm] - Homo sapiens
created	[InstanceEdit:9759187] Rothfels, Karen, 2021-11-29
dbId	9759185
displayName	Positive gene expression regulation by 'NQO1 gene:p-AcK-NFE2L2:CHD6:MAFK [nucleoplasm]'
modified	[InstanceEdit:9944271] Rothfels, Karen, 2025-04-03
regulatedEntity	[BlackBoxEvent:R-HSA-9759186] AcK-NFE2L2- dependent NQO1 gene expression - Homo sapiens
regulator	[Complex:R-HSA-9759114] NQO1 gene:p-AcK-NFE2L2:CHD6:MAFK [nucleoplasm]
schemaClass	PositiveGeneExpressionRegulation

(regulation)	[RegulationReference:9759183] Positive gene expression regulation by 'NQO1 gene:p-AcK-NFE2L2:CHD6:MAFK [nucleoplasm]' An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
(regulatedBy)	[BlackBoxEvent:R-HSA-9759186] AcK-NFE2L2- dependent NQO1 gene expression

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