Reactome | Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV

Schema > Reaction > Entries

Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV Show undefined attributes

authored	[InstanceEdit:749521] Dall'Olio, GM, 2009-11-10
catalystActivity	[CatalystActivity:975927] alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity of MGAT4s [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:975912] Jassal, B, 2010-10-08
dbId	975903
displayName	Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV
edited	[InstanceEdit:975912] Jassal, B, 2010-10-08
eventOf	[Pathway:R-HSA-975577] N-Glycan antennae elongation - Homo sapiens
input	[SimpleEntity:R-ALL-975910] NGP [Golgi lumen] [SimpleEntity:R-ALL-914003] UDP-GlcNAc [Golgi lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1015720] Kinetic properties and substrate specificities of two recombinant human N-acetylglucosaminyltransferase-IV isozymes [LiteratureReference:1015718] Aberrant expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer [LiteratureReference:1015781] N-glycan alterations are associated with drug resistance in human hepatocellular carcinoma [LiteratureReference:1015762] Cloning and characterization of the human UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV-homologue (hGnT-IV-H) gene
maxDepth	1
modified	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
name	Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV
orthologousEvent	[Reaction:R-BTA-975903] Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV - Bos taurus [Reaction:R-DME-975903] Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV - Drosophila melanogaster [Reaction:R-GGA-975903] Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV - Gallus gallus [Reaction:R-XTR-975903] Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV - Xenopus tropicalis [Reaction:R-DRE-975903] Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV - Danio rerio [Reaction:R-SSC-975903] Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV - Sus scrofa [Reaction:R-CFA-975903] Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV - Canis familiaris [Reaction:R-RNO-975903] Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV - Rattus norvegicus [Reaction:R-MMU-975903] Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV - Mus musculus
output	[OtherEntity:R-ALL-981616] Glycoprotein with GlcNAc in position 4 [Golgi lumen]
releaseDate	2010-12-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1028799] Gagneux, P, 2010-11-18
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-975903
summation	[Summation:1015749] N-acetylglucosaminyltransferase (GnT)-IV catalyzes the addit...

Referrals

(hasEvent)

[Pathway:R-HSA-975577] N-Glycan antennae elongation