Reactome | SARS-CoV-1 8b binds to IRF3

Schema > Reaction > Entries

authored	[InstanceEdit:9731030] Stephan, Ralf, 2021-05-11
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9731037] Stephan, Ralf, 2021-05-12
crossReference	[DatabaseIdentifier:12020764] Mondo:0005091
dbId	9731077
disease	[Disease:9678120] severe acute respiratory syndrome
displayName	SARS-CoV-1 8b binds to IRF3
edited	[InstanceEdit:9815358] Stephan, Ralf, 2022-08-17
eventOf	[Pathway:R-HSA-9692916] SARS-CoV-1 activates/modulates innate immune responses - Homo sapiens
input	[EntityWithAccessionedSequence:R-COV-9678168] 8b [cytosol] [EntityWithAccessionedSequence:R-HSA-166251] IRF3 [cytosol]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9731068] Accessory proteins 8b and 8ab of severe acute respiratory syndrome coronavirus suppress the interferon signaling pathway by mediating ubiquitin-dependent rapid degradation of interferon regulatory factor 3
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SARS-CoV-1 8b binds to IRF3
output	[Complex:R-HSA-9731017] IRF3:8b [cytosol]
relatedSpecies	[Species:9678119] Human SARS coronavirus
releaseDate	2022-09-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9713569] D'Eustachio, Peter, 2021-01-26
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9731077
summation	[Summation:9731083] SARS-CoV-1 protein 8b binds to Interferon regulatory factor ...

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