Reactome | NPM1(1-117)-ALK(1068-1620) fusion [cytosol]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-HSA-9700080] ALK fusion proteins [cytosol] - Homo sapiens
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9730700] NPM1(1-117)-ALK(1068-1620) fusion dimer [cytosol] - Homo sapiens [Complex:R-HSA-9730700] NPM1(1-117)-ALK(1068-1620) fusion dimer [cytosol] - Homo sapiens
created	[InstanceEdit:9730698] Rothfels, Karen, 2021-05-10
crossReference	[DatabaseIdentifier:12021285] Mondo:0018908
dbId	9730697
disease	[Disease:6802338] lymphoma [Disease:1500689] cancer [Disease:2328081] non-Hodgkin lymphoma
displayName	NPM1(1-117)-ALK(1068-1620) fusion [cytosol]
endCoordinate	117
hasModifiedResidue	[FragmentInsertionModification:9730695] Insertion of residues 1068 to 1620 at 118 from UniProt:Q9UM73 ALK
inDisease	true
literatureReference	[LiteratureReference:9730688] Molecular detection of the (2;5) translocation of non-Hodgkin's lymphoma by reverse transcriptase-polymerase chain reaction
maxDepth	1
name	NPM1(1-117)-ALK(1068-1620) fusion Nucleophosmin B23 NPM_HUMAN
referenceEntity	[ReferenceGeneProduct:uniprot:P06748] UniProt:P06748 NPM1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9730697
startCoordinate	1

(hasCandidate)	[CandidateSet:R-HSA-9700080] ALK fusion proteins [cytosol]
(hasComponent)	[Complex:R-HSA-9730700] NPM1(1-117)-ALK(1068-1620) fusion dimer [cytosol]

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