Reactome | IgE binds omalizumab

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IgE binds omalizumab Show undefined attributes

authored	[InstanceEdit:9725212] Stephan, Ralf, 2021-03-29
category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:9724683] Jassal, Bijay, 2021-03-25
dbId	9724685
definition	Binding
displayName	IgE binds omalizumab
edited	[InstanceEdit:9725212] Stephan, Ralf, 2021-03-29
eventOf	[Pathway:R-HSA-2454202] Fc epsilon receptor (FCERI) signaling - Homo sapiens
input	[Complex:R-HSA-1591211] IgE [extracellular region] [ProteinDrug:R-ALL-9724689] omalizumab [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9724679] Pharmacokinetics, pharmacodynamics and safety of QGE031 (ligelizumab), a novel high-affinity anti-IgE antibody, in atopic subjects [LiteratureReference:9725207] Omalizumab (Xolair) for treatment of asthma
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	IgE binds omalizumab
orthologousEvent	[Reaction:R-GGA-9724685] IgE binds omalizumab - Gallus gallus [Reaction:R-SSC-9724685] IgE binds omalizumab - Sus scrofa [Reaction:R-BTA-9724685] IgE binds omalizumab - Bos taurus [Reaction:R-CFA-9724685] IgE binds omalizumab - Canis familiaris [Reaction:R-RNO-9724685] IgE binds omalizumab - Rattus norvegicus [Reaction:R-MMU-9724685] IgE binds omalizumab - Mus musculus
output	[Complex:R-HSA-9724684] IgE:omalizumab [extracellular region]
releaseDate	2021-06-09
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9725667] Niarakis, Anna, 2021-03-31
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9724685
summation	[Summation:9725209] When bound to the high-affinity IgE receptor (FCERI), IgE ac...

Referrals

(hasEvent)

[Pathway:R-HSA-2454202] Fc epsilon receptor (FCERI) signaling

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