Reactome | IgE binds omalizumab

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10818726
displayName	IgE binds omalizumab
eventOf	[Pathway:R-GGA-2454202] Fc epsilon receptor (FCERI) signaling - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9724685] IgE binds omalizumab - Homo sapiens
input	[Complex:R-GGA-1591211] IgE [extracellular region] [ProteinDrug:R-ALL-9724689] omalizumab [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	IgE binds omalizumab
output	[Complex:R-GGA-9724684] IgE:omalizumab [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-9724685
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-GGA-2454202] Fc epsilon receptor (FCERI) signaling
(inferredTo)	[Reaction:R-HSA-9724685] IgE binds omalizumab

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