Reactome | p-Y IRS1:ALK fusion proteins [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9712075] Rothfels, Karen, 2021-01-14
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	9712076
disease	[Disease:1500689] cancer
displayName	p-Y IRS1:ALK fusion proteins [cytosol]
hasComponent	[CandidateSet:R-HSA-9713536] IRS- and FRS-binding ALK fusion proteins [cytosol] [EntityWithAccessionedSequence:R-HSA-74772] p-Y-IRS1 [cytosol]
inDisease	true
isChimeric	false
literatureReference	[LiteratureReference:9699651] Characterization of the transforming activity of p80, a hyperphosphorylated protein in a Ki-1 lymphoma cell line with chromosomal translocation t(2;5)
maxDepth	4
modified	[InstanceEdit:9730949] Rothfels, Karen, 2021-05-12
name	p-Y IRS1:ALK fusion proteins
producedByEvent	[Reaction:R-HSA-9712082] ALK fusions phosphorylate IRS1 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9712076
updateTrackers	[UpdateTracker:9902756] Update Tracker - [Complex:9712076] p-Y IRS1:ALK fusion proteins [cytosol] - v78:[updateContainedComponent]

(updatedInstance)	[UpdateTracker:9902756] Update Tracker - [Complex:9712076] p-Y IRS1:ALK fusion proteins [cytosol] - v78:[updateContainedComponent]
(output)	[Reaction:R-HSA-9712082] ALK fusions phosphorylate IRS1

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