Reactome | ATIC(1-229)-ALK(1058-1620) fusion [cytosol]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-HSA-9700080] ALK fusion proteins [cytosol] - Homo sapiens
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9710898] ATIC(1-229)-ALK(1058-1620) fusion dimer [cytosol] - Homo sapiens [Complex:R-HSA-9710898] ATIC(1-229)-ALK(1058-1620) fusion dimer [cytosol] - Homo sapiens
created	[InstanceEdit:9710827] Rothfels, Karen, 2021-01-05
crossReference	[DatabaseIdentifier:12020842] Mondo:0020325 [DatabaseIdentifier:9711757] COSMIC:COSF444
dbId	9710829
disease	[Disease:9699595] anaplastic large cell lymphoma
displayName	ATIC(1-229)-ALK(1058-1620) fusion [cytosol]
endCoordinate	229
hasModifiedResidue	[FragmentInsertionModification:9710828] Insertion of residues 1058 to 1620 at 230 from UniProt:Q9UM73 ALK
inDisease	true
literatureReference	[LiteratureReference:9710743] ATIC-ALK: A novel variant ALK gene fusion in anaplastic large cell lymphoma resulting from the recurrent cryptic chromosomal inversion, inv(2)(p23q35)
maxDepth	1
modified	[InstanceEdit:9711951] Rothfels, Karen, 2021-01-13
name	ATIC(1-229)-ALK(1058-1620) fusion Bifunctional purine biosynthesis protein ATIC PUR9_HUMAN
referenceEntity	[ReferenceGeneProduct:uniprot:P31939] UniProt:P31939 ATIC
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9710829
startCoordinate	1

(hasCandidate)	[CandidateSet:R-HSA-9700080] ALK fusion proteins [cytosol]
(hasComponent)	[Complex:R-HSA-9710898] ATIC(1-229)-ALK(1058-1620) fusion dimer [cytosol]

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