Reactome | GSDME(1-270) W44C [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9710398] Shamovsky, Veronica, 2020-12-30
crossReference	[DatabaseIdentifier:12020833] Mondo:0005061
dbId	9710470
disease	[Disease:1500689] cancer [Disease:8853117] lung adenocarcinoma
displayName	GSDME(1-270) W44C [cytosol]
endCoordinate	270
hasModifiedResidue	[ReplacedResidue:9710419] L-tryptophan 44 replaced with L-cysteine
inDisease	true
literatureReference	[LiteratureReference:9710028] Gasdermin E suppresses tumour growth by activating anti-tumour immunity
maxDepth	1
memberOf	[CandidateSet:R-HSA-9710467] GSDME variant [cytosol] - Homo sapiens
name	GSDME(1-270) W44C Gasdermin-E (1-270) W44C Gasdermin-E, N-terminal
referenceEntity	[ReferenceGeneProduct:uniprot:O60443] UniProt:O60443 GSDME
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9710470
startCoordinate	1

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