Reactome | KPNA2:6 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Schema > Complex > Entries

compartment	[Compartment:6791047] endoplasmic reticulum-Golgi intermediate compartment membrane
created	[InstanceEdit:9705291] Shamovsky, Veronica, 2020-10-22
crossReference	[DatabaseIdentifier:12020746] Mondo:0100096
dbId	9705285
disease	[Disease:9683912] COVID-19
displayName	KPNA2:6 [endoplasmic reticulum-Golgi intermediate compartment membrane]
hasComponent	[EntityWithAccessionedSequence:R-COV-9705293] 6 [endoplasmic reticulum-Golgi intermediate compartment membrane] [EntityWithAccessionedSequence:R-HSA-205976] KPNA2 [cytosol]
inDisease	true
includedLocation	[Compartment:70101] cytosol
isChimeric	false
literatureReference	[LiteratureReference:9705074] Evasion of Type I Interferon by SARS-CoV-2
maxDepth	2
name	KPNA2:6
negativelyRegulates	[NegativeRegulation:9757522] Negative regulation by 'KPNA2:6 [endoplasmic reticulum-Golgi intermediate compartment membrane]'
producedByEvent	[Reaction:R-HSA-9705299] SARS-CoV-2 6 binds KPNA2 - Homo sapiens
relatedSpecies	[Species:9681683] Severe acute respiratory syndrome coronavirus 2
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9705285

(regulator)	[NegativeRegulation:9757522] Negative regulation by 'KPNA2:6 [endoplasmic reticulum-Golgi intermediate compartment membrane]'
(output)	[Reaction:R-HSA-9705299] SARS-CoV-2 6 binds KPNA2

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